Malignant Vasovagal Syncope

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Vasovagal syncope and vasovagal disease.

(Hellenic Journal of Cardiology) HJC ñ 61 I solated vasovagal syncope (VVS) is not a disease, but rather the clinical manifestation of an autonomic reflex to which all (or almost all) individuals are predisposed. Why certain subjects appear to be more susceptible than others to the development of paradoxical hypotension and bradycardia, and why the event occurs at one time and not another, rema...

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Malignant Vasovagal Syncope: Physiopathology, Diagnosis, Epidemiology, and Medical Treatment

The encouraging results from the "Inotropy Controlled Pacing in Vasovagal Syncope" (INVASY) Italian multicenter clinical trial – which demonstrated the effectiveness of pacing based on Closed Loop Stimulation (CLS, Biotronik, Germany) in preventing vasovagal syncope (VVS) [1,2] – provided us incentive to prepare a review entitled "Malignant Vasovagal Syncope." The review provides an updated rev...

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Malignant vasovagal syncope: a randomised trial of metoprolol and clonidine.

OBJECTIVE To evaluate the efficacy of head up tilt guided treatment with metoprolol and clonidine in preventing the recurrence of syncope in patients with malignant vasovagal syncope. PATIENTS 20 patients (9 men and 11 women, mean age 33 (SD 17), range 14 to 62 years) with severe symptoms. DESIGN Randomised double blind crossover trial; efficacy was assessed by head up tilt testing. RESUL...

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Vasovagal syncope interrupting sleep?

Clinical data are reported for 13 patients who were referred with recurrent loss of consciousness at night interrupting their sleep. Most of the patients were women (10 of 13) with a mean age of 45 years (range 21-72 years). The histories were more consistent with vasovagal syncope than with epilepsy. This was supported by electroencephalographic and tilt test results. More polysomnographic mon...

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Recurrent Postural Vasovagal Syncope

Background—The pathophysiology of vasovagal syncope is poorly understood, and the treatment usually ineffective. Our clinical experience is that patients with vasovagal syncope fall into 2 groups, based on their supine systolic blood pressure, which is either normal ( 100 mm Hg) or low (70–100 mm Hg). We investigated neural circulatory control in these 2 phenotypes. Methods and Results—Sympathe...

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ژورنال

عنوان ژورنال: Circulation

سال: 2003

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.0000068033.19278.f1